desbarajustar

Means to throw something into disarray or mess up an established order — el cambio de último minuto desbarajustó todos los planes (the last-minute change threw all the plans into chaos). It's related to the noun desbarajuste (mess, chaos), which is arguably even more common than the verb itself.

• La lluvia desbarajustó todos nuestros planes. — The rain threw all our plans into disarray.
• Un solo error desbarajustó el cronograma completo. — A single mistake threw off the entire schedule.
• No quiero desbarajustar tu organización. — I don't want to mess up your organization.

It's informal-to-neutral in register, not vulgar or slang — but in very formal writing, desorganizar or desordenar reads as more polished than desbarajustar, which keeps a slightly colloquial flavor.