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6,713 words — headwords with part of speech, pronunciation, and a plain-language definition.

desafiante: defier; challenge (a person who is difficult to handle or work with)
desafiantemente: defiantly
desafiar: to challenge (in a competition); to defy, to challenge (e.g. parents, a leader, the status quo); to brave; to call out (i.e. to criticize or expose)
desafilado: dull (edge)
desafilar: to unsharpen; to dull; to blunt
desafiliación: disaffiliation
desafiliar: to disassociate, to disaffiliate
desafinación: detuning; getting out of tune
desafinar: to sing or play out of tune
desaforadamente: outrageously; wildly, out of control
desaforado: wild, uncontrolled, outrageous
desaforar: to deprive of (a privilege or immunity)
desafortunadamente: unfortunately; regrettably
desafortunado: without luck; unfortunate
desafuero: outrage, violence; excess; impeachment
desafío: challenge; defiance, provocation
desagarrar: to let go; to release
desagotar: to drain
desagradable: unpleasant, disagreeable, distasteful, off-putting, displeasing, unpleasing, bad, rude, unsavory, uncomfortable, unlikable, objectionable, painful, uncongenial, crappy, gnarly (US slang); nasty, ugly, unkind, objectionable, unsightly (e.g., person, behavior)
desagradablemente: unpleasantly
desagradar: to displease, be disagreeable
desagradecer: to be unthankful for, to be unappreciative of
desagradecido: thankless
desagrado: displeasure, distaste, disliking, dislike
desagraviar: to make amends
desagravio: amends, atonement
desagredecimiento: ingratitude
desagregación: disintegration
desagregar: to disintegrate; to disaggregate
desaguadero: drain
desaguador: synonym of desaguadero
desaguar: to drain; to waste; synonym of orinar
desaguisado: outrageous
desaguisado: outrage; mess
desagüe: drainage, gutter
desahijar: to separate young cattle from their mothers
desahogadamente: comfortably
desahogar: to unburden, to relieve; to vent, to rant, to violently express one's feelings; to blow off steam, to let off steam, to pour one's heart out, to get off one's chest
desahogo: relief (solace); outlet (release of emotions or desires)
desahuciar: to evict; to give up (a lost cause, a terminal patient etc.)
desahucio: eviction
desainar: to remove fat from; to thin
desairado: humble; unhaughty; underrated
desairar: to snub; to slight; to offend
desaire: snub; slight
desajustar: to upset; to disarrange, disorder, clutter; to be out of adjustment, disadjust, misadjust (adjust or set wrongly); to be out of adjustment, go out of adjustment, disadjust, misadjust (lose adjustment)
desajuste: bad adjustment; mismatch; imbalance
desalación: desalination
desaladora: desalination plant
desalar: to desalinate
desalar: to clip the wings from
desalentado: dejected
desalentador: discouraging
desalentar: to discourage; to become discouraged
desaliento: dejection
desalineación: misalignment
desalineado: out of order
desalineamiento: unalignment
desalinear: to misalign
desalinización: desalinization